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Coulbourn Instruments scrambled grid floor shocker model e13-08
Scrambled Grid Floor Shocker Model E13 08, supplied by Coulbourn Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/grid+floor+shocker/grid+floor+shocker/us11969460-163-18-23
Average 90 stars, based on 1 article reviews
scrambled grid floor shocker model e13-08 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats.
Article Snippet: We examined whether treatment with sildenafil citrate (the active compound of Viagra), a cyclic nucleotide phosphodiesterase type 5 inhibitor (PDE5), would reverse the learning impairment induced by cholinergic muscarinic (mACh) receptor blockade [0.75 mg/kg scopolamine HCl, intraperitoneal (i.p.) injections].. Rats were pretrained in a one-way active avoidance of foot shock in a straight runway and the next day received 15 training trials in a 14-unit T-maze.. Performance in this maze paradigm requires accurate responding to avoid mild foot shock and has been shown to be sensitive to aging and to impairment in central cholinergic systems.

Article Title: Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition.
Article Snippet: Rationale: The nitric oxide (NO)–cyclic guanosine monophosphate (cGMP) signal transduction pathway has been implicated in some forms of learning and memory.. Recent findings suggest that inhibition of phosphodiesterase (PDE) enzymes that degrade cGMP may have memory-enhancing effects.. Objectives: We examined whether treatment with sildenafil citrate, a PDE type 5 inhibitor, would attenuate a learning impairment induced by inhibition of NO synthase [60 mg/kg N-nitro-L-arginine methyl ester (L-NAME), i.p.].

Article Title: Striatal Lesions Interfere with Acquisition of a Complex Maze Task in Rats
Article Snippet: The runway had a grid floor comprised of stainless steel bars that were wired to receive scrambled shock (alternating current) from a Coulbourn Instruments (E13-08) grid floor shocker.

Article Title: Passive avoidance and complex maze learning in the senescence accelerated mouse (SAM): age and strain comparisons of SAM P8 and R1.
Article Snippet: Two strains of the senescence accelerated mouse, P8 and R1,were tested in footshock-motivated passive avoidance (PA; P8, 3–21 months; R1, 3–24 months) and 14-unit T-maze (P8 and R1, 9, and 15 months) tasks.. For PA, entry to a dark chamber from a lighted chamber was followed by a brief shock.. Latency to enter the dark chamber 24 hours later served as a measure of retention.

Article Title: Nitric oxide and carbon monoxide have a stimulatory role in the hypothalamic-pituitary-adrenal response to physico-emotional stressors in rats.
Article Snippet: Electroshocks (1 mA, 1 sec duration, randomized to two shocks per min for 45 min) were delivered to the animal’s paws using a Coulbourn E13–08 grid floor shocker controlled by a Macintosh computer (44).

Article Title: Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitro-L-arginine methyl ester.
Article Snippet: In a previous study, our laboratory reported that sildenafil citrate, a cyclic nucleotide phosphodiesterase type 5 inhibitor, reversed a learning impairment in rats induced by systemic inhibition of nitric oxide synthase (60 mg/kg, i.p., N-nitro-L-arginine methyl ester; L-NAME).. To limit the peripheral effects of L-NAME and further localize the site of action of sildenafil, L-NAME (48 μg, i.c.v.) was infused bilaterally into the lateral cerebral ventricles 30 min prior to maze training.. Saline or sildenafil citrate (1.5 or 3.0 mg/kg, i.p.) was administered systemically 15 min before training.

Generated:

Article Title: Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Deficit in Fear Response and Conditioned Taste Aversion
Article Snippet: .. Electric shock was generated by a grid floor shocker that was controlled by the HABITEST Universal Linc using L2T2 Operant Control Software (Coulbourn Instruments). ..

Control:

Article Title: Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Deficit in Fear Response and Conditioned Taste Aversion
Article Snippet: .. Electric shock was generated by a grid floor shocker that was controlled by the HABITEST Universal Linc using L2T2 Operant Control Software (Coulbourn Instruments). ..

Software:

Article Title: Metabotropic Glutamate Receptor Subtype 7 Ablation Causes Deficit in Fear Response and Conditioned Taste Aversion
Article Snippet: .. Electric shock was generated by a grid floor shocker that was controlled by the HABITEST Universal Linc using L2T2 Operant Control Software (Coulbourn Instruments). ..



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